Synthetic Oral Mucin Mimic from Polymer Micelle Networks
نویسندگان
چکیده
منابع مشابه
Synthetic Oral Mucin Mimic from Polymer Micelle Networks
Mucin networks are formed in the oral cavity by complexation of glycoproteins with other salivary proteins, yielding a hydrated lubricating barrier. The function of these networks is linked to their structural, chemical, and mechanical properties. Yet, as these properties are interdependent, it is difficult to tease out their relative importance. Here, we demonstrate the ability to recreate the...
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Mucin networks are viscoelastic fibrillar aggregates formed through the complex self-association of biopolymeric glycoprotein chains. The networks form a lubricious, hydrated protective shield along epithelial regions within the human body. The critical role played by mucin networks in impacting the transport properties of biofunctional molecules (e.g., biogenic molecules, probes, nanoparticles...
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ژورنال
عنوان ژورنال: Biomacromolecules
سال: 2014
ISSN: 1525-7797,1526-4602
DOI: 10.1021/bm5006917